OmiGenomics está comprometido a desarrollar herramientas de Medicina de Precisión que tengan el fundamento científico que sustenten su validez y utilidad clínica. Para los Kits Tricogenética se revisaron bases de datos y artículos científicos publicados en revistas indexadas con el fin de reunir y seleccionar la información para determinar los genes y polimorfismos analizados en la prueba genética.
Les presentamos las referencias bibliográficas más importantes que forman parte del fundamento científico de los Kits Tricogenética.
Referencias revelantes que forman parte del sustento de Tricogenética:
Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness (Heilmann-Heimbach et al., 2017) https://pubmed.ncbi.nlm.nih.gov/28272467/
Genetic prediction of male pattern baldness (Hagenaars et al., 2017) https://pubmed.ncbi.nlm.nih.gov/28196072/
GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk (Pirastu et al., 2017) https://pubmed.ncbi.nlm.nih.gov/29146897/
Genetic basis of male pattern baldness (Nyholt et al., 2003) https://pubmed.ncbi.nlm.nih.gov/14675213/
Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia (Hillmer et al., 2005) https://pubmed.ncbi.nlm.nih.gov/15902657/
Hair growth is promoted by BeauTop via expression EGF and FGF-7 (Lee et al., 2018) https://pubmed.ncbi.nlm.nih.gov/29693180/
Human sulfotransferases and their role in chemical metabolism (Gamage et al., 2006) https://pubmed.ncbi.nlm.nih.gov/16322073/
Pharmacogenetics of SULT1A1 (Daniels & Kadlubar, 2014) https://pubmed.ncbi.nlm.nih.gov/25493573/
Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride (Huskey et al., 1995) https://pubmed.ncbi.nlm.nih.gov/8654202/
Sequence diversity in CYP3A5 promoters and characterization of the genetic basis of polymorphic CYP3A5 expression (Kuehl et al., 2001) https://pubmed.ncbi.nlm.nih.gov/11279519/
The rs776746 variant of CYP3A5 is associated with intravenous midazolam plasma levels and higher clearance in critically ill Mexican paediatric patients (Flores-Pérez et al., 2021) https://pubmed.ncbi.nlm.nih.gov/33638195/
The role of vitamins and minerals in hair loss: a review (Almohanna et al., 2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380979/
Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P-induced human mast cell activation and degranulation in the hair follicle (Jadkauskaite et al., 2018) https://pubmed.ncbi.nlm.nih.gov/29859202/
IL-18 and cutaneous inflammatory diseases (Lee et al., 2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691115/
Characterizing genetic variants for clinical action (Ramos et al., 2014) https://onlinelibrary.wiley.com/doi/10.1002/ajmg.c.31386